Characterization of Vernix Caseosa: Water Content, Morphology, and Elemental Analysis

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The biology of vernix caseosa.

The biology and physical properties of the uniquely human skin cream 'vernix caseosa' are discussed. This material coats the foetal skin surface during the last trimester of gestation and provides multiple beneficial functions for the foetus and newborn infant. Vernix has a complex structure similar to stratum corneum but lacks lipid lamellae and is more plastic due to the absence of desmosomal...

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Barrier properties of vernix caseosa.

Experiments are described which show that vernix caseosa has a mechanical barrier effect if it is deposited in an unbroken layer. Specific antibacterial properties were not detected in vernix. It is suggested that vernix is best left on a newborn infant because of its mechanical obstruction to bacterial passage.

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Vernix Caseosa Peritonitis After Vaginal Delivery

INTRODUCTION Vernix caseosa peritonitis (VCP) is a very unusual complication caused by inflammatory response to amniotic fluid spilled into the maternal peritoneal cavity. Twenty-seven cases have been reported, and all occurred after cesarean section. CASE PRESENTATION We present a case of VCP following vaginal delivery; this may be the first case reported after vaginal delivery. Mrs. A, 28 y...

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Delayed presentation of vernix caseosa peritonitis

INTRODUCTION Vernix caseosa peritonitis (VCP) is a rare and poorly recognised condition resulting from a sustained foreign body reaction to the vernix caseosa of the baby. This case-based review aims to highlight its importance for any medical team managing patients with peritonitis who have undergone a recent Caesarean section. CASE REPORT A 31-year-old woman presented 5 weeks after a Caesa...

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Epidermal barrier lipids in human vernix caseosa: corresponding ceramide pattern in vernix and fetal skin.

BACKGROUND Vernix caseosa is a protective biofilm covering the fetus during the last trimester. Vernix and epidermal barrier lipids (i.e. cholesterol, free fatty acids and ceramides) appear to share protective functions for fetal and neonatal skin. OBJECTIVES To analyse vernix samples for epidermal barrier lipid content, and to compare lipid profiles of vernix with those of fetal and postnata...

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 2000

ISSN: 0022-202X

DOI: 10.1046/j.1523-1747.2000.00134.x